Evidence of Platelet Dysfunction in Congenital Cyanotic Heart Disease: Relevance to Palliative Systemic-Pulmonary Shunt and Haemostatic Parameters

Document Type : Abstracts

Abstract

Abnormal platelet function has been hypothesized to play 
a role in the haemostatic abnormalities in cyanotic 
congenital heart disease (CCHD) patients. Blood platelets 
in patients with CCHD were occasionally characterized 
by significantly enhanced expression of P-selectin in 
resting circulating platelets as well as their augmented 
activation in response to stimulating agents.